Bacteria & Gum Disease also promotes Heart Disease

Science Update

The same bacteria that cause gum disease also promotes heart disease

Gum disease bacteria may cause heart disease. This could change the approach that cardiovascular disease is diagnosed and treated. Although doctors know that patients with gum disease are at a greater risk for heart disease gum disease is not considered a traditional risk factor for heart disease.

In a recent study researchers infected mice with four bacteria that cause gum disease and tracked their spread. Once the bacteria were identified in the gum of mice heart and aorta scientists saw an increase in risk factors including cholesterol and inflammation associated with heart disease. 

It is important to pay careful attention to oral health in order to protect patients against heart disease.

Structured Silver is a highly effective antimicrobial. When silver has been structured into water it allows the water molecule to get absorbed into the blood stream and pass through the circulation. It gets excreted unchanged which means no harmful metabolites are formed. It has the ability to enter a single red blood cell enabling the silver to travel through capillaries and inactivate viruses at the cellular level. It has been shown to kill drug-resistant bacterial strains and inhibit viral replication. In addition silver acts an anti-inflammatory provides immune support and does not encourage resistant microbial strains.

Source: American Society for Microbiology.Gum disease bacteria may cause heart disease.

Beauty from the Inside Out – (405) 888-5614 https://zen-medspa.com
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Botox Special at Zen-Medspa

Zen Aesthetics Medspa is running a special in the month of January 2019 on Botox Wrinkle Eraser. Here is the deal. When you buy 20 Units for $260 you will get 10 more units free. This is a savings of $130! You can purchase more than 20 units if you need. A typical procedure for the lines between the forehead is 16-20 Units. This leaves a few more units to inject in your forehead for those lines you want to go away. You can call and schedule an appointment at 405-679-3854. Zen Aesthetics and Wellness has 5 star ratings on Google and Yelp. While your there check out the other laser and skincare services they offer. They are reasonably priced.

Zen-Medspa.com

Vitamin D/Metabolism/Magnesium

Science Update

Vitamin D status and metabolism are influenced by magnesium status according to new study

Healthcare providers know the importance of assessing the vitamin D status of their patients. When vitamin D levels are low, supplementation is recommended, or the dosage may be increased if they’re already supplementing. Accumulating research demonstrates the intricate interrelationships between vitamin D and other nutrients. It’s important to maintain optimal levels of all the fat-soluble vitamins, but let’s not forget magnesium.

According to a new randomized trial published earlier this month in the American Journal of Clinical Nutrition, researchers demonstrated that magnesium influences vitamin D status. Magnesium had a regulatory effect, with magnesium deficiency essentially shutting down the vitamin D synthesis and metabolism pathway.

The research team became interested in a role for magnesium because people respond to vitamin D differently, with levels of the vitamin in some individuals not rising even after being given high dosage supplements.

This randomized study included 250 patients 40 to 85 years of age at risk for developing colorectal cancer due to having had a precancerous polyp removed or having other risk factors. Doses of magnesium and placebo were customized based on baseline dietary intake.

Magnesium supplementation increased 25-OH vitamin D levels but not 1,25 dihydroxyvitamin D when baseline levels were less than 30 ng/mL, but decreased both in a dose-dependent manner when levels were between 30 to 50 ng/mL . As a result, optimal magnesium status is important and plays a role in optimizing vitamin D status.

Insufficiencies of both vitamin D and magnesium are common among patients. Over 75% of individuals have a calcium-to-magnesium ratio greater than 2.5, and up to 80% of people do not consume enough magnesium in a day to meet the recommended dietary allowance (RDA). Most of these individuals are also vitamin D deficient.

Patients should be advised to consume foods rich in magnesium and/or vitamin D, such as dark leafy greens, beans, whole grains, dark chocolate, fatty fish such as salmon, nuts, and avocados. Foods that provide vitamin K2, such as aged cheeses, organ meats, and egg yolks, can help protect against the vascular calcification that may result from high-dose vitamin D supplementation in the absence of adequate vitamin K2.

By Michael Jurgelewicz, DC, DACBN, DCBCN, CNS

Zen-Medspa.com

We offer Designs for Health Vitamins and can measure your carotenoid score which tells us how many anti-oxidants are in your system and if your vitamins are working for you. We have the Pharmanex Scanner which is a Nobel Prize Winning device at Zen Aesthetics and Wellness, 122 N Bryant Ave. Edmond, OK 73034  (405)888-5614

HGH Transdermal Gel – Somaderm

New U Life’s Homeopathic SOMADERM Gel is the only transdermal human growth hormone (HGH) product available without a prescription.  The molecular breakdown of HGH found in Somaderm Gel is a synthetic USP human growth hormone (somatropin).

Available at Zen Aesthetics & Wellness Medspa in Edmond.  405-679-3854. HGH injections cost between $1,800 and $2,000/month which is not very practical for most individuals.  Your HGH levels start dropping at about the age of 25 and the older you are the lower your levels.  Somaderm is a homeopathic product that increases your HGH levels slowly.  Most people can tell a difference within a few weeks after using the gel.  It is available at Zen Medspa for $169.99/bottle.  We also have the Pharmanex Biophotonic Scanner that measures carotenoids in the skin. We have found that the scanner also responds to higher levels of HGH.  The Raman Spectroscopy technology used by the Biophotonic Scanner is a Physics Nobel Prize winning technology recognized by scientific articles and studies. We can do pre and post scans to evaluate your carotenoid level which is an indicator of antioxidants in your body.  If you are interested in the product or a scan visit Zen Medspa at 122 N Bryant Ave. Edmond, OK 

HGH Somaderm Gel

Human Growth Hormone (HGH) transdermal gel.zenaestheticsandwellness.com

 

 

Octoberfest Event Friday Oct 6th 1-6pm

ZenAestheticsAndWellness Oct Event

Please come – Fall Event at Zen Aesthetics Medspa, Friday October 6th from 1-6pm
122 N Bryant Ave. #B1, Edmond, OK

Enjoy Food, Fun and Lots of Special Pricing for Skin Care Treatments on the Day of The Event! We are offering Free Shiatzu Foot and Back Massage, Free LED Light Treatment, Free Chi machine Treatment, Free Hand Paraffin Treatment, Demonstration of Body Contouring, Free Samples of Designs for Health Supplement Pure Paleo Protein Shake. Visit with Owners and employees of Zen and Skin Care Representatives! See you there! Char
Oct Event

A new review demonstrates the role of the gut microbiome in autism spectrum disorders

Posted on Fri, Jun 23, 2017 @ 06:52 AM

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Autism spectrum disorder (ASD) has an unclear cause but is associated with various genetic, neurologic, metabolic, and immunologic factors. Although there is no definitive treatment, gastrointestinal symptoms are common in patients with autism. Such patients who present GI symptoms may show significant behavioral manifestations, including anxiety, self-injury and aggression.

In a recent review in Frontiers in Cellular Neuroscience, researchers review the bidirectional interactions between the central nervous system (CNS) and the gastrointestinal tract via the brain-gut axis, and the role of the gut microbiota in the CNS and ASD.

This review of over 150 papers on ASD and gut bacteria found that, since the 1960s, researchers have been reporting on the association between the composition of gut microbiome and autistic behavior. It highlights many studies which have shown that restoring a healthy balance in gut bacteria can help ASD symptoms.

Research demonstrates that the gut microbiota is associated with ASD symptoms (directly or indirectly), in part by altering the immune system and metabolism. Studies show a higher percentage of intestinal permeability in ASD patients, resulting in a higher antigenic load from the gastrointestinal tract. These inflammatory cytokines are present in the circulation and cross the blood-brain barrier. Alterations in the composition of the gut microbiota and their metabolic products are commonly observed in patients with ASD. For example, lipopolysaccharide (LPS) is increased in the serum of ASD patients and is associated with impaired social behavioral scores.

In addition, the gut microbiome of children with ASD is less diverse with lower levels of Bifidobacterium and Firmicutes and higher levels of Lactobacillus, Clostridium, Bacteroidetes, Desulfovibrio, Caloramator and Sarcina. Also, children with autism who present gastrointestinal symptoms have lower abundances of the genera Prevotella, Coprococcus, and Veillonellaceae, and higher levels of the Clostridium histolyticum group. The reduction of Clostridium results in significant improvements with ASD symptoms.

Researchers found that Candida was twice as abundant in ASD. The dysbiosis seen in ASD results in the expansion of Candida, leading to further imbalance and an exacerbation in abnormal behaviors.

Early life events can alter the composition of the gut microbiome in ASD patients. These may include the overuse of antibiotics, maternal obesity and diabetes during pregnancy, how a baby is delivered, and if and how long the infant was breastfed. Keep in mind that a child under three years of age whose brain is at the height of development may have impaired neurodevelopment due to the presence of the metabolic products resulting from the dysbiosis and intestinal permeability.

As I stated earlier, at present, there is no definitive treatment or cure for ASD. However, there are certain diet and nutritional therapies that offer help, such as a gluten-free and casein-free (GFCF) diet. Many of these children have a dysbiosis and opportunistic infections; thus, it is essential to assess their gut health. As described, children with ASD have significantly different concentrations of certain bacteria in their stool compared to children without ASD. It is suspected that gut microbes can alter the levels of neurotransmitter-related metabolites, affecting the gut-to-brain communication and altering brain function.

By Michael Jurgelewicz, DC, DACBN, DCBCN, CNS

New study demonstrates sulforaphane helps to improve glucose control in patients with type 2 diabetes

Posted on Fri, Jun 16, 2017 @ 10:08 AM

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According to a study published two days ago, researchers demonstrated that sulforaphane improves fasting glucose levels and decreases HbA1c levels in patients with type 2 diabetes.

Metabolic syndrome and insulin resistance are significant health care problems in the United States. Type 2 diabetes affects more than 300 million people, and up to 15% of patients cannot take the medication metformin because of kidney damage risks. As a result, researchers sought out to identify compounds that may inhibit disease-associated gene expression changes seen with type 2 diabetes.

The researchers constructed a signature for type 2 diabetes based on 50 genes, then used publically available expression datasets to screen 3,852 compounds for drugs that potentially reverse the disease. They demonstrated that sulforaphane reduced glucose production by liver cells growing in culture and altered liver gene expression away from a diseased state in diabetic rats.

Researchers then gave 97 patients with type 2 diabetes a concentrated broccoli sprout extract (BSE) for 12 weeks. As result, BSE reduced fasting glucose in patients with dysregulated type 2 diabetes but not in patients with well-regulated type 2 diabetes. They also observed an association between body mass index and BSE-induced change in HbA1c. There were significantly reduced levels of HbA1c after BSE treatment in obese patients with dysregulated type 2 diabetes. BSE was also more effective in lowering fasting blood glucose in patients with elevated triglyceride levels and in patients with high HOMA-IR. The BSE-induced reduction of HbA1c correlated with high fatty liver index.

These results demonstrate that sulforaphane reduces glucose production by NRF2 translocation and decreased expression of key gluconeogenetic enzymes and improves fasting glucose and HbA1c in obese patients with dysregulated type 2 diabetes. Sulforaphane reduces glucose production by mechanisms different than metformin and also protects against diabetic neuropathy, renal failure, and atherosclerosis due to its antioxidative effects.

There are several additional nutrients that can play a role in improving insulin signaling such as chromium, zinc, carnosine, benfotiamine, alpha lipoic acid, and inositol. Also, essential fatty acids should be consumed for overall health, but most individuals with insulin resistance are deficient. Fish oils improve insulin sensitivity and reduce inflammation.

While insulin resistance continues to be a major health issue in the US, it is preventable and reversible through lifestyle changes, exercise, stress management, and proper nutrition and supplements. Weight loss and exercise are considered among the best treatments for restoring the body’s ability to respond to insulin.

By Michael Jurgelewicz, DC, DACBN, DCBCN, CNS